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Baby rule (piefed.cdn.blahaj.zone)
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[-] artifex@piefed.social 160 points 1 week ago

Remember folks, taking too much Tylenol WILL destroy your liver and kill you fairly quickly.

[-] 9point6@lemmy.world 65 points 1 week ago

And don't take it the morning after a heavy night of drinking, it's like 10x more toxic in that scenario.

If you need a pain killer go for ibuprofen until like 24h after you finished your last drink

[-] Battle_Masker 19 points 1 week ago
[-] Mouselemming@sh.itjust.works 26 points 1 week ago

Tylenol and alcohol are both processed through the liver and can harm it, especially when taken together, whereas ibuprofen ....

Okay I went to Wikipedia to check on the safety of ibuprofen with alcohol (bad idea, can cause gastric bleeding, just don't combine painkillers and booze in general) and I found out two (2) different things I found very interesting:

"Unlike most other NSAIDs, ibuprofen also acts as an inhibitor of Rho kinase and may be useful in recovery from spinal cord injury.[59][60] Another unusual activity is inhibition of the sweet taste receptor.[61]"

Hopefully I'll not need the first fact, but I'm all for anything that helps those who do.

And as a person with weight issues it's useful to me to know that second one so I don't sabotage myself!

[-] 9point6@lemmy.world 10 points 1 week ago* (last edited 1 week ago)

Yeah that's a good call, definitely don't smash the ibuprofen, but I think one dose is generally pretty low risk, given I believe you still need to be overdosing on the ibuprofen to get problems, at least that's what a doctor told me when I asked a number of years ago.

The thing with alcohol and paracetamol/acetaminophen is it causes your liver to do something different than if you had the two separately. I'm not 100% I'm getting the terminology exactly right here but, If alcohol is taking up all of the "usual" enzyme a less efficient enzyme processes the paracetamol that's less efficient at metabolising it, that enzyme produces a toxic by-product that normally isn't created. That toxic by-product is what causes the liver failure if it can't subsequently be metabolised again quick enough.

[-] kerrigan778 4 points 1 week ago* (last edited 1 week ago)

A lot of things increase your risk of GI bleeding, it is a very serious danger but it's something you have to look at combinations of risk factors. I take high dose zoloft which increases my risk of GI bleeding and I drink socially, I never take more than a fairly low dose of ibuprofen or aspirin after drinking and I never take more than 200 mg of ibuprofen every 2 hours when not drinking, so far so good.

[-] HeyThisIsntTheYMCA@lemmy.world 3 points 1 week ago* (last edited 1 week ago)

iirc the GI bleed risk is a standard NSAID thing. They cause your gastric and intestinal linings to grow slower, and since you need to constantly replenish that mucus. if it's not thick enough you get an ulcer.

standard not a doctor this isn't medical advice blahblah

[-] jaybone@lemmy.zip 8 points 1 week ago

It can damage your liver. Though some say it is greatly exaggerated when this discussion pops up online. But still I wouldn’t risk it.

I think advil/motrin is a safer NSAID if you are a drinker.

Liver failure is a fairly slow death taking up to a month

[-] artifex@piefed.social 23 points 1 week ago

Ok I didn’t mean like gunshot quick more like “get your affairs in order” quick.

Correction: It will start killing you quickly, but the actual death will be long and painful. Liver failure is a particularly bad way to go out.

[-] fuckgod@feddit.online 7 points 1 week ago

Man, Trump looks like he could use a night out drinking and then hangover relief with Tylenol.

[-] criss_cross@lemmy.world 14 points 1 week ago

My favorite stat about the safety seals is that you’re much more likely to die taking Tylenol than from someone poisoning your Tylenol.

[-] latenightnoir 12 points 1 week ago

Is that a threat, or a promise?😏😏

[-] Zizzy 17 points 1 week ago

Its really painful and not quick.

[-] latenightnoir 6 points 1 week ago
[-] Cevilia 3 points 1 week ago

A little from column A. A little from column B. And a hell of a way to go out that I wouldn't wish on my worst enemy either.

[-] latenightnoir 0 points 1 week ago

Really gotta stop with this kinky talk, doin' me no good:))

[-] Midnitte@beehaw.org 5 points 1 week ago

As will corn, chocolate, and water.

[-] MML@sh.itjust.works 4 points 1 week ago

Take ibuprofen instead and destroy your intestines instead!

[-] Zoomboingding@lemmy.world 40 points 1 week ago

Yeah this is a joke I can't get behind because not everyone knows how dangerous this is

[-] OldChicoAle@lemmy.world 12 points 1 week ago* (last edited 1 week ago)

Hot take: Americans don't know how dangerous this is. Every day I am reminded just how fucking dumb the average American is. A land of degrading intelligence. Our president loves the poorly educated, just like our elected officials do!

[-] BadJojo 29 points 1 week ago

So many layers to this joke, and they are all now federal crimes.

[-] CheesyFox@lemmy.sdf.org 11 points 1 week ago

this joke is too american for me to understand

Doctors and scientists in my country assured everyone that paracetamol (tylenol) is fine and to ignore whatever the US is doing :P

But for your information Trump announced that paracetamol during pregnancy causes autism.

[-] CheesyFox@lemmy.sdf.org 8 points 1 week ago

ah, i see, another day, another cause of autism. What a fucking clown.

[-] OrteilGenou@lemmy.world 4 points 1 week ago

Clowns are another cause of autism, probably

[-] CheesyFox@lemmy.sdf.org 2 points 1 week ago

i'm afraid, our biggest concern should be a dangerous airborne chemical compound, called dioxygen. It spreads everywhere, and autism is on the mild side of possible effects caused by this lethal chemical weapon. I heard it even caused a great extinction once.

Username checks out

[-] EffortlessEffluvium@lemmy.zip 5 points 1 week ago

You wanna give that kid autism!?!

[-] Geodad@lemmy.world 5 points 1 week ago

That's enough tylenol to do massive damage to your liver, if taken in a single dose. It would likely put you in the hospital or kill you.

[-] ChairmanMeow@programming.dev 11 points 1 week ago

No, it wouldn't. These are likely 500mg pills, and there's 7 of them. That's 3.5g worth, well below the daily recommended limit of 4g and well below the 10g single dose limit for adults where toxicity becomes likely. Even if these were the chonky 1g pills, it's not likely to cause liver damage.

[-] DragonTypeWyvern@midwest.social 2 points 1 week ago
[-] Geodad@lemmy.world 1 points 1 week ago

Lol yes.

What is pictured is basically a whole day worth of Tylenol. It is enough to initiate liver failure, if taken in a single dose.

[-] OrteilGenou@lemmy.world 2 points 1 week ago

No, this is a hyper autistic dose, but it won't cause death unless there's a bible nearby

[-] DragonTypeWyvern@midwest.social 2 points 1 week ago

If that makes you feel better

[-] Phineaz@feddit.org 2 points 1 week ago

Depends on the concentration. Yes Paracetamol can absolutely kill you if taken in grand excess. But this would have to be a very high dosage per pill to get you that far. Still not healthy of course.

they're shaped like mini bomb pops so they have to be good

this post was submitted on 23 Sep 2025
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