Their bites aren't as bad as you might think. They can fuck you up, but they rely on pretty quick attacks, so the risk is more in repeated strikes(from what we've seen with the limited coyote attacks that happen).

Don't recommend going for a straight-on brawl, but if you can get behind one, you might have a chance. Bonus points, they're naturally pretty disinclined to fight a human unless given no other options, so you might be able to slip behind at a point?