13
Quick question (self.mtf)
submitted 9 hours ago by birdwing to c/mtf

When using tablets, are you supposed to take them with a sip of water (if oral), or not?

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[-] Nikki 7 points 9 hours ago

most do yeah, I know some dissolve the pill under their tounge to bypass some liver(?) issues but do research before trying

[-] Filetternavn 4 points 9 hours ago

Sublingual administration has a dramatic effect on both bioavailability and half-life. With a half-life of merely 2 hours (compared to 13 via oral), you need to take 3-4 doses per day, and your dosage would need to be adjusted. I would never recommend someone use sublingual directly in place of their oral, as once daily sublingual administration is absolutely not a good idea

[-] PanGodofPanic 3 points 7 hours ago

I did once daily sublingual for like, 3 years. Switched to twice daily fairly recently and have noticed zero difference.

this post was submitted on 26 May 2026
13 points (100.0% liked)

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