article doesnt present any pressure they are facing. also
Drug production costs are often shrouded in secrecy with little clarity on how they relate to prices, if at all.
Prices are never about cost, its what people are willing to pay. Which gets brutally exploited by pharmaceutical industry.
Literally almost every drug in existance.
Then after the parent rubs out, they make a slightly different version and repatent it.
Insulin: new formula now 0.0005% more effective for only 9000% increase in profit!
Every neighborhood should have community drug labs (not just the sheriff's meth lab like we have now) and every pharma researcher should be spilling their guts or spilling their guts.
Meanwhile volvo assigns the patent for the 3-point seatbelt to the public domain because it will save countless lives.
A Swedish company not being evil? What are they, the opposite of America?
Novo Nordisk is a Danish company, not American.
We were talking about Volvo.
Right. But based on context clues, it's implied that the full meaning of the post was "Volvo did something for the public good, therefor Volvo is good. Volvo is a Swedish company. Swedish companies are good. Sweden is in Europe. European countries are good. American countries are bad. Novo Nordisk did something bad. It must be an American company."
Admittedly, my mistake was not being more clear about the point of my response which is that geography is irrelevant - capitalism and all companies are evil (or at best, amoral).
You didn’t have a clarity issue
That was in no way what I was saying, which about U.S. companies pretty much never doing the right thing and European companies actually doing that sometimes.
Well you see… there’s the yacht, the yacht they have to land the helicopter, and the smallish yacht they use to go into port because berths at dock are hard to come by.
Oh and the. There’s the helicopter, the pilots, the mansion in every state. Except, uh, the ones that tax rich people.
It’s all part of the cost…
Have you seen all those hoes and bitches that get on those yachts and they all got their titties out and showing their ass and pussy. It's a great trickle down economy Ronny put together.
You forgot the biggest expense; the billions of dollars in stock buybacks.
Double pop! First time I've seen a privacy popup on top of a privacy popup. The top one you can only accept.
CAD$650/month in Canada. I've lost 36 Kg (80 lbs) and I'm still losing weight. My blood work shows no signs of diabetes, my cardiac indicators are also excellent, but my hemoglobin is low because I don't eat beef anymore (not because of the Ozempic, I haven't been able to digest it for about six years.) I'm taking an iron supplement to build it back up.
Ozempic sucks until you stop fighting it. After that it's an easy ride.
I'm wearing an XL t-shirt and large sweat pants today down from 3XL in both eight months ago.
Any side effects?
It acts by slowing down the emptying of your stomach. That means that whatever you eat stays in your stomach for many hours. If you eat too much at night or something that is acidy or spicy it causes terrible heart burn and reflux/regurgitation. I take an omeprazole with sodium bicarbonate at bedtime to relieve the acid.
I eat a granola bar or a couple of eggs for breakfast then a small bowl of whatever is on offer for dinner and that's it. My stomach is never empty. Sometimes, if I want to have something spicy or acidy I will have it for breakfast. I've had a fajita for breakfast and I once had chicken parm for breakfast. Then I eat something easy for dinner.
The most upsetting side effect was the fact that I went from a daily bathroom guy to every three or four days. I was eating so much less and my body was making such good use of what I ate that I just didn't produce much. It can cause constipation but you need to avoid taking laxatives because you can become dependant. Just drink lots of water, eat lots of fiber, and walk a lot and you will be fine.
If you fight it it's going to make you miserable. If you lean in you will lose a lot of weight fast. I've lost so much weight so quickly that my body freaks me out a bit. When I'm sitting on the edge of the bed and look down at my legs I don't recognize them. I told someone a few weeks ago that I just wanted a little candy because I'm fat and she said, "No you're not."
On the plus side I mentioned to my doctor that I was getting shorter (in in my late 50s and went from 5' 10 1/2" to 5' 9 1/2" and he asked, "Your penis?" I said, "No, that's getting longer!" He laughed and said, "It was hiding." I've actually gained an inch and a half of useable penis. (That's a happy side effect.)
Ozempic sucks until you stop fighting it. After that it’s an easy ride.
Are there plateaus like with other weight loss?
I'm not eating any solid food due to a medical issue (long story) and I have lost 80 pounds as well. My weight can drop very quickly sometimes, as much as a pound every few days. Other times, like recently, it takes a long time to go down. It's taken me a good two months to go from 190 to 180, whereas I was 260 at the start of January 2023.
If not eating enough period causes plateaus, I would think Ozempic would as well.
I plateaued in the low 220s for a month or so then the weight fell off me to the low 200s. I'm creeping down now at about half a pound per week. My ultimate goal was to get to 200 lbs but I'm now thinking that I may go to 190 lbs since the weight is continuing to come off. I don't want to go lower than that. I don't want to be a thin person. I just want to be less fat.
There’s a lot of mistrust with drug makers at the moment, for good reason and this is a great article on the breakdown of costs. They do have a point about recouping the cost of R&D but maybe they should be more transparent about how long it’ll take them to do so. MBAs are very good at pulling levers to make money, they just don’t think about the human element, which is the most important lever.
Two points about R&D costs:
First, they aren't just trying to make up what they spent on this treatment, but others that failed during research/trials. There's a lot of them the general public will never hear about, and pharmas generally don't like to bring attention to their failures. Part of that is many shareholders are morons who don't understand how science works.
Second, the costs can get fuzzier for larger companies who in-house much of the R&D process, since the costs get shared among many programs. Properly attributing spend in that case can be a serious challenge.
All that said, they've clearly seen an opportunity to rake it in with this trendy drug and are charging way more than they need to.
If these were nonprofit companies and all employees were paid at/below market rates I would not complain.
It is the profit and CEO pay that I object to.
Guys our government is broken.
As I read that they charge just 155 bucks in other countries I guess the high price lies in not having a suitable health care system. You can't have both, calling other countries socialists or communists AND having good health care by having the same contracts that we have. Sorry.
$1500. That's how much eight weeks of ozempic costs for me if I had to pay out of pocket.
How much to get people together to steal the recipe and set up a lab?
Bet its less than a five year supply, which is probably just a week or two between a group og interested parties!
I honestly don't get why so many people are so upset.
I get it with things like insulin where we know how to make it for years. But a new revolutionary drug? Sure their production cost is low but that doesn't include R&D and just think of how many drugs don't work. That's why when we do find something that works we can't expect it to only pay for itself, it has to make enough buck to basically pay for them as well, because why else even bother?
Most pharma R&D is actually done by the government. Unless they can prove it's an outlier there....
The government funds the first phase of the search. This is very important. But beyond that, the bill is footed by private sector.
A quote from this study:
The federal government is the primary funder of basic research in biomedical sciences through the National Institutes of Health (NIH). This research is essential for informing all medical progress, including the development of therapies. Overall, 54% of basic science milestones are achieved by the public sector and 27% by the private sector. From that point onward, taking the necessary risks associated with the drug development process required to advance basic science research into safe and effective treatments for patients corresponds primarily to the biopharmaceutical industry. Performing Phase I through IV clinical trials consumes more than 90% of total research and development (R&D) cost.
A number of recent studies indicate that a majority of this R&D is funded by investments made by the private sector.1 In a 2019 report, Research America indicated that, in 2016, the private sector funded 67% of total U.S. medical and health R&D while the federal government supported 22%.
The NIH is not immune to poison pill studies financed by the industry. Research America is the for-profit health industry with a mask on. It was also physically conducted by at least one member of a political think tank that lobbies for government payouts to corporations, (PPI). Then there's this gem at the end-
This research was supported by funding from the Pharmaceutical Research and Manufacturers of America (PhRMA), Amgen Inc., The Biotechnology Innovation Organization (BIO), GlaxoSmithKline, Novartis International AG, Sanofi S.A., and Pfizer Inc.
Maybe, instead of leaning on opinion pieces written by the industry you should look at actual research done by PHDs.
Like this direct comparison done for 2010-2019 finding industry breaks even with the government at it's most forgiving calculation. And at worst the government is shouldering 90 percent of the costs.
I'm diabetic, and also have a few mental health issues. The doc took me off Ozempic, citing it's side affects of messing with mental health.
Sorry to hear it. What sort of side effects were there?
Doc said risks were reported of adversely affecting PTSD, depression, and suicidal thoughts.
Oh wow. Yeah, definitely a good idea to stop taking it. I'm glad you're still with us and I hope you've found a good solution!
Thanks, I'm doing pretty well. But I don't need a drug with those side effects. I mention this primarily because these side effects appear to be largely unreported, while the drug is being widely marketed for weight loss. People should be aware of the risks.
Seriously, no kidding but sometimes I think that people are still discovering capitalism
Guy looks like Bill Gates without hair.
So why didn't anyone else start manufacturing it for $5 about 15 years ago then?
Patents most likely.
Interestingly its always libertarian types defending patents; rather than being against it for being government intervention.
In either case patents and copyright need reform for today's economy.
And a lot of people in my country are hoarding lots of Ozempic shots. Please remember this is for DIABETICS, and not for everyday weight loss.
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