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submitted 3 days ago by florencia to c/mtf

I'm already on Estradiol monotherapy with sublingual pills. My new dealer wanted to start me on 3mg of Estradiol Cypionate per week. I asked instead for 4mg/week of Estradiol Cypionate which accepted. But per https://transfemscience.org/articles/transfem-intro/ it looks like I should have asked for 5mg of Cypionate weekly to start, and fine tune from there.

Has anybody had success for monotherapy on 4mg/week? The calculators on the website show a mid-slope of 225 pg/mL. For 5mg/week it's 275 pg/mL.

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[-] Filetternavn 3 points 2 days ago

I've had success with 3mg/week of EC as monotherapy for well over a year. It all depends on your body

this post was submitted on 27 Jul 2026
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