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submitted 10 months ago* (last edited 10 months ago) by MicroWave@lemmy.world to c/health@lemmy.world

A combination shot would make it easier for people to get vaccinated against Covid and the flu at the same time.

Moderna’s combined Covid and flu shot outperformed the existing standalone vaccines for both viruses, according to the results of a phase 3 clinical trial published Wednesday in theJournal of the American Medical Association

The vaccine uses the same messenger RNA technology as Moderna’s approved Covid vaccine.(There are no approved mRNA-based flu shots.)

The trial, funded by Moderna, included more than 8,000 adults ages 50 and older who were enrolled in October and November 2023. For people ages 50 to 64, the new vaccine was compared to Moderna’s Covid vaccine and the flu shot Fluarix. For people 65 and older, it was compared to the Covid vaccine and a different flu shot, called Fluzone, which is a stronger dose typically given to older adults. The trial participants either got the existing shots, or the new combination vaccine plus a placebo shot. (This way, both groups got two injections.)

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[-] uawarebrah@sh.itjust.works 51 points 10 months ago

I can’t wait. I love Vaccines. Science is truly amazing.

[-] prole 11 points 10 months ago

I know right? We need more comments like this to counter all the anti-vax bullshit.

I'm not just neutral on vaccines, I think they're fucking amazing and I want more.

[-] jagged_circle@feddit.nl 4 points 10 months ago

I don't think we're going to find antivaxxers on Lemmy.

[-] nieceandtows@programming.dev 3 points 10 months ago

I'm not antivax but I'm suspicious of these 'subscription' vaccines which don't eradicate the disease but only succeed in helping them mutate every year so that they can keep lining their pockets. Don't we have the scientific advancements to eradicate flu instead of playing a profitable cat and mouse every year? I'm from India, and was very surprised to hear about the annual flu shots when I first came to the US. May be I'm just cynical, and there is just no way to truly eradicate flu accounting for its mutations.

[-] GoodLuckToFriends@lemmy.today 1 points 10 months ago

‘subscription’ vaccines which don’t eradicate the disease but only succeed in helping them mutate every year

Alright... I'm trying to be nice here, but what exactly do you know about vaccines, and more importantly, viruses?

[-] k0e3@lemmy.ca 2 points 10 months ago

Ugh, there seems to be one in this very thread. So sick of them (no pun intended).

[-] Ledericas@lemm.ee 1 points 10 months ago* (last edited 10 months ago)

they are all still shilling on reddit, youtube, ,,,etc.

[-] ours@lemmy.world 9 points 10 months ago

The closest things to miracles we can actually do! Preserving probably millions of lives every year. It used to be normal to have a bunch of kids and just have many of them die or get crippled early in live due to child illness.

Fun fact: in Vietnam, after they kicked out the French, they changed all the French street names with some exceptions. Pasteur was one of those exceptions.

[-] Treczoks@lemmy.world 19 points 10 months ago

... unless you are in a country with a crazy antivaxxer at the helm of public health.

[-] fadingembers 11 points 10 months ago

Does this mean we're still getting a flu shot this year in the US? Last I heard RFK cancelled everything for them

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[-] 0101100101@programming.dev 9 points 10 months ago* (last edited 10 months ago)

The trial, funded by Moderna

We did a trial which decided the governments around the world need to give us lots of money again and are releasing this information to drive up share price.

[-] higgsboson@dubvee.org 10 points 10 months ago* (last edited 10 months ago)

Trials are how drugs get approved and made. The article has a link to the study. If you disagree with the science, by all means, please elaborate.

I understand you want to display cynicism towards both drug companies and governments. Would you prefer they not offer this vaccine for sale? Personally, I'd prefer just the one shot because I usually get both, but you do you.

[-] MirthfulAlembic@lemmy.world 6 points 10 months ago

What did you think was going to happen? Another company or university would graciously fund and conduct a trial of Moderna's product for no reason?

If conducting a regulated clinical trial and having the results independently reviewed by government agencies in each market they seek to enter is not sufficient, I think you've already made up your mind.

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[-] prole 3 points 10 months ago

I'm no expert on drug trials, but I'm relatively sure they contract that shit out to competent firms.

[-] 0101100101@programming.dev 2 points 10 months ago
[-] prole 6 points 10 months ago

Yes, and...?

[-] turmacar@lemmy.world 6 points 10 months ago* (last edited 10 months ago)

A company going through the regulatory trial and approval process is not evidence of wrongdoing or bribery. The problem wasn't Boeing paying for the fuel and pilots to test planes, it was that they said "we promise we tested everything and it was good" and nobody looked at the paperwork.

[-] jagged_circle@feddit.nl 3 points 10 months ago* (last edited 10 months ago)

Who else would pay for it?

Are you aware of any countries that will dish out money to drug companies to trial their drugs?

If so, I'll start an LLC and a lab. I gotta whole lotta drugs I'd like to try out. And no shortage of friends who'd love to work full time on the government payroll to try a bunch of expiermental drugs..

[-] ieatpwns@lemmy.world 7 points 10 months ago

Not if the brain worms have anything to say about it

[-] eddanja@lemmy.world 4 points 10 months ago

Oh HELL nooo! Not on Worm-Brain's watch!!

[-] fireweed@lemmy.world 1 points 10 months ago* (last edited 10 months ago)

Side effects such as fever and chills were more common in people who got the new vaccine.

This caveat, glossed over in the article, is potentially a huge drawback.

Personally, the covid and flu shots by themselves make me feel icky but moderately functional for 24-36 hrs, but the time I had both at once I was practically bedridden for three days.

Obviously not everyone has this problem, but from what I've heard it's common enough that I worry if the two-in-one shot becomes the new standard it will turn a lot of folks off from vaccination altogether. There's enough vaccine hesitancy and skepticism out there already that a miserable reaction (or simply the need to clear your schedule for three whole days) could be enough to cause folks to indefinitely postpone their yearly booster or forgo vaccination altogether.

[-] Ledericas@lemm.ee 3 points 10 months ago

only the og first covid made me feverish,achey, plus the pain from the vaccine. that lessened over time as you get more shots.

[-] Akuchimoya@startrek.website 4 points 10 months ago

Everyone reacts differently to different things. I know someone who's side effects were worse each Covid shot he got. He still got them, because he was taking care of an elderly family member, but he had to started planning to be bedridden himself. He's not antivax, but stopped getting boosters when the family member died because he didn't want to be laid up for a week at a time.

[-] RememberTheApollo_@lemmy.world 2 points 10 months ago

I find the Moderna vaccine in general (covid only) makes me feel worse than the Pfizer one. No idea why, but making it worse won’t prevent me from getting vaccinated, I’ll just get separate vaccines.

As long as people have choices, and they know what they are, it shouldn’t be a big deal. The problem will arise when people don’t know/have a choice and feel like crap when given the combo vax.

[-] jagged_circle@feddit.nl 1 points 10 months ago

Maybe try the vaccine from China. It does nothing

[-] 0101100101@programming.dev 1 points 10 months ago

This caveat, glossed over in the article, is potentially a huge drawback. I've known people who have been floored after just one of the vaccines. Though I wonder if the body reacts differently to the combined than two singles.

[-] Ledericas@lemm.ee 2 points 10 months ago

i mean the MMR-v and tdap have been in use for decades, which are vaccines of multiple viruses, antigens as one.

covid just illicit a stronger immune reaction, because of how newly humans encountered the coronavirus.

[-] gearheart@lemm.ee 1 points 10 months ago

So... Whats this about covid shot causing heart problems? Propaganda or true?

I imagine having full COVID causes more heart and lung problems than the shot ever would.

[-] RememberTheApollo_@lemmy.world 6 points 10 months ago

Yes.

It has reportedly caused myocarditis in some people, and they generally recover.

However:

for every 100 000 vaccinated, compared to about four more cases of myocarditis we have 56 fewer hospitalizations, 13.8 admissions to intensive care and 0.6 fewer deaths.

https://pmc.ncbi.nlm.nih.gov/articles/PMC9653149/

this post was submitted on 08 May 2025
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