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Is 0.12ml injected weekly enough?
(self.mtf)
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this post was submitted on 15 Oct 2023
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It really depends on the concentration. I've seen anywhere between 10mg/mL and 40mg/mL. So if your vial is 10mg/mL, you'd only be getting 1.2mg/week which does seem pretty low to me. If your vial is 40mg/mL then your weekly dose would be 4.8mg which seems more reasonable. Really though it all depends on how your levels are, when was your last blood test?
It's also important to note when in your injection cycle you tested. I'm mostly interested in what my trough values will be (so immediately prior to the next injection), since that's the best approximation of steady state tissue levels. Especially on a two week injection cycle of EV, I'd be worried about my levels dipping quite low by the end of the cycle.
What concerns come with levels dropping?
For me personally, I got mood swings right before my next dose until I changed the frequency because my levels would drop. But in general, the goal with feminizing hrt is to change your hormone profile to something approximating that of a cis woman in order to get the changes you want. With a long enough gap between doses, the short half life of EV means that you'll have very low levels of estrogen right before your next injection, below your goal range.