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Transfem
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From the sources that I'd read. It's not clear that prog will help boost feminization but to me it helps and have benefits.
Here's my take from testing. (Went from 100 mg to 200 because the pharmacy made an error and gave me more :p).
(Rectal is the best way to have the best effects, oral made me a bit eepy, and but higher "soothing" effect)
Noticeable effect for me 1 : libido (went up but could be due to external factors)
2 : breast growth increased (them again I don't have a way to compare if I hadn't)
3 : mood. I feel better with it in general (then again could be linked to external factors too)
4 : smell (my armpit smell changed with prog)
5 skin? I haven't noticed much about that. Maybe a little bit of acne started but it stopped soon after.
I'm going to find the article (backed by scientific researches). I've read about it that sums up quite clearly what to expect or not.
Another thing about the wait of 1 or 2 years before taking progesterone is unfounded to me. Honestly I started month 3 and see only benefits on my end.
As for administration technique. I do rectal when I feel it's "ok". Otherwise orally with water. I use some lube for rectal administration.
As for your syndrome. I have no clue sadly.
im a 13 months on E, so is not early