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please note, this much HRT at once would probably be a lethal dose
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Doesn't overdosing cause blood clots? I feel like that would complicate the assessment since enough to cause blood clots might not be instantly lethal, but a stroke, or heart attack because of it absolutely can be lethal.
I honestly don't know if blood clots are an acute risk of your hormones are spiked that high or a chronic risk from long term high hormone levels.
I actually assumed the method it kills you would be liver failure as it struggled to return your body to homeostasis.