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this post was submitted on 23 Dec 2024
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TechTakes
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Big brain tech dude got yet another clueless take over at HackerNews etc? Here's the place to vent. Orange site, VC foolishness, all welcome.
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Unfortunately actually working in bio/med didn't go well despite training for it aggressively and working her ass off given that she graduated at the perfect time to compete for entry-level positions with recently laid-off people with 5+ years of experience. Between that and chronic illness in the family will all the associated experience with the failings of our medical system I'm actually pretty sympathetic to the biohackers from a purely ideological perspective, but these people are just begging for a disaster.
Beyond reading through and enthusiastically agreeing with everything you had, she did say that if you're working on anything consumable or injectable using 3D printed parts at all is going to be a red flag. Your first two pieces of equipment should be an autoclave and a fume hood, at which point you're better off working with all glass for durability and not melting reasons. Making your work space actually sterile and sufficiently free of contaminants to do any of this jnt be first place is also going to be a pain, require a lot of tape and curtains and the like, and probably not work as well as you'd want.
Also even working in a proper university lab with a fume hood and climate controls you still get sufficiently different results that the mk1 eyeball is utterly insufficient for identification. You'll learn worse than nothing.
I keep having to remind a couple of my friends who got 3D printers for themselves as gifts that 3D printed parts aren’t ever food safe, much less whatever standard’s required to make safe injectables. specifically, bacteria likes to hide inside the layer lines on FDM parts, and resin parts are made of a material that shouldn’t be ingested or introduced into your bloodstream
on chemistry side, i guess you can wing it a bit and not strictly require fume hood in low population density area. not having rotovap, at best with appendages (chiller + chemical resistant vacuum pump, aspirator gives limited capability) makes all but simplest syntheses deeply unserious to impossible especially if you want to do some analysis later. especially if it's IR and melting point because solvents fuck up both