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this post was submitted on 05 Aug 2024
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TechTakes
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Big brain tech dude got yet another clueless take over at HackerNews etc? Here's the place to vent. Orange site, VC foolishness, all welcome.
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Regarding the paper "Discovery of a structural class of antibiotics with explainable deep learning", a comment by e. e. arroyo:
i'm not reading all that, at least now, but i'd just notice that carboxylic acids are notoriously terrible at crossing membranes unless some trickery is used, so there could be massive issues downstream. issues that, you know, can be effortlessly pruned at early stage of drug development
I do remember part of the appeal for SETI@home back in the day was the ability to analyze the data that heuristics had ruled out but not conclusively, so it's not like there's no precedent. Of course the other benefit of BOINC was using the "spare" cycles in consumer hardware rather than purpose-building more massive power and water-hungry datacenters, so the cost was arguably negligible even if the benefits were similarly small.
"for SBV values of explaining"