Absolutely a real thing. https://www.hopkinsmedicine.org/-/media/files/allchildrens/clinical-pathways/chs_pathway-2025-08-18.pdf

https://www.gastrojournal.org/article/S0016-5085%2824%2900127-6/

https://jamanetwork.com/journals/jama/fullarticle/2824833

https://gastro.org/clinical-guidance/diagnosis-management-of-cannabinoid-hyperemesis-syndrome/

https://my.clevelandclinic.org/health/diseases/21665-cannabis-hyperemesis-syndrome

Wikipedia: 45 sources cited

Raises hand meekly... I do in fact get this if I've been consistent for a long-ass time, not necessarily the dose size, but I swear to god you could replace my pen with ipecac and it would be the same experience. That said, long breaks "reset" it for me.

And while I don't personally know anyone with the same problem, there are thousands of stories both online and IRL for me of "friend of a friend can't smoke weed anymore because of it".

Its extremely well documented. This is exactly why you shouldnt take medical advice online seriously. It just stems from an over saturation of cannaboid receptors. The same receptors whose antiemetic effects are useful for cancer patients or other nausea prone patients can be reversed by over saturation of the receptor. It can be fixed typically by a period of abstinence that lets the receptors reset, but some people can never really partake again.

I say this as someone who worked as a nursing assistant and used to be an anatomy/biology tutor in college. I also have smoked way more weed than any of you over the past decade. If you havent seen any evidence of this, its because you have no idea how to look.

Pretty sure this is actually a real thing, however this Philadelphia Inquirer bit is def written like propaganda

estimated 32% prevalence among cannabis users

113 cases documented worldwide

never heard of it despite your social circle being mostly daily smokers of high-thc weed

Lol definitely not a propaganda thing, and all of us 339 pot smokers should be worried

Yeah, legalization widens the sample group of users effectively, which will cause rarer symptoms to appear among people who have sensitivities to things they wouldn't otherwise have known

I would bet it happens more among people who overconsume edibles, which definitely became more accessible after legalization

I smoked 4 huge cones to the dome today in between vapes. And that’s just joints. I know a lot of people that smoke weed. Never seen this.

I do think it’s propaganda. I’ve seen doctors write people immediately off and blame the weed if they tell the truth. Like people with the fucking flu not taken seriously and told it was smoking weed. Some people will blame all sorts of things if they get sick.

Call your doctor if a scrommit lasts longer than four hours, though!

Let's see, wake up, dab, scromit, eat potato, drink coffee, brush teeth, dab, do homework, scromit, go to class, go to work, come home, dab, do more homework, scromit, brush teeth, go to bed.

Phew, just made it on a normal day!

Combustion products are always bad for your lungs, but cigarettes supposedly have stuff in them that is uniquely bad and especially carcinogenic.

I get what you're trying to say. But the image OP displayed is actually propaganda. I get the feeling a lot of people don't know what propaganda means and think it's only something a government does to make you a gungho patriot.

If the argument, info, message, whatever form of communication being delivered to you, is designed to appeal to your emotions, or sway your opinion, even if it contains some mote of truth, it's propaganda. Smokey the Bear is propaganda. To guilt you into not starting forest fires. It's for a decent cause, but it's no less a mascot designed to alter the behaviour of the populace.

Well, I had been smoking almost all day every day for a decade, the last year I was hitting dab at least 3 times per day. The weekend of the incident, i ate an early breakfast, drove for 6 hours, then went backcountry camping with what I thought was enough food/water (I was wrong) and a too much thc. Went all day with very little food/water, hitting a 2g vape every few minutes and walked around 17 miles. Then my friend drove us the 6 hour drive home, about an hour later I got a ride to the hospital, I usually drive myself to the hospital but I could barely move. I dont mess with that stuff or anything else anymore. Being clean feels better anyway.

Great resource link! I poached it get the LD50 for delta-9 tetrahydrocannabinol which is the psychoactive property the plant has been bred for. That number is actually higher at 1270 mg/kg.

And as you stated, it would have to be 100% purity concentrate in a vein.

That's why cannabis fear mongering is utter nonsense. Yes, there can be seriously deleterious effects for heavy, chronic users. But unless you're really trying, a toxic dose is almost impossible.