The inconsistent backround,

the cutoff text in the second panel,

that every panel is slightly different but featuring the same content(for example the "He" on helium is very slightly different in every panel, a regular artist would copy paste the text, not draw it every frame),

the font not being consistent(Look at the "E" in "HELIUM WALKS" and then the "E" in "WE DON'T"),

the absence of period symbols(Image Generation LLMs love to do this)

and the artstyle is very specific to other AI comics that are currently floating around the net.

Inconsistent bsckground shelving

On top of everything others have said, there's no watermark, signature, url, etc from an original artist. Webcomics like this will always have one unless it's removed by a reposter, which yeah, that happens, but I feel not as often these days. And when it does, it's a pretty shitty thing to do, and not a good situation either.

the font, all ChatGPT produced "memes" use the same "font"

Another thing not mentioned is how when you zoom in on solid colors you see compression artefacts. Generative AI hates solid colors and sharp lines, so they often have slight imperfections

Inconsistencies. The bottles are different in every panel. The door is missing after the first panel despite not being any closer to the bar. The scale is way off from the other two in the last panel. The bar fades out of existence in the last panel, and the wall panel is gone. The text being cut off on the edge of the second panel.

Amongst all the other tells pointed out. The most obvious one right now is whats dubbed “AI-sans font”

There is atm only a single generator that can make this quality though. All ai generators have their unique quirks you learn to identity.

Same yellow-ish pallette

Some things got me suspicious. Some patterns, the art style, the colors are "a strange choosing".. everything is so "overly perfect" except for the letters that feel kind of off... like someone had to unfuck the text. Besides, this is some polished artwork for a random comic with no firm.

But the real give away for me are the bottles

Bottles in the background change every panel

Ratio

Inconsistency of the backgrounds is another big hint. A human would have just copy/pasted it.

the font, I have seen a lot of these AI generated memes on socials and the font is almost always the same (it has inconsistencies but the style is the same)

This is the n-th so-called "AI" created comic that's posted in this style. Alsog as others have noted: inconsistent style/background between the panels.

There have been quite a few comics in this style recently. For this specific comic, the background is always changing.

I and 12 others at this moment do. If that doesn't help, then imagine a group of thirteen of us, in person, where your joke made the whole group laugh.