Someone mentioned Patriot here the other day, and I think that qualifies as at least lesser-known.
Also going to plug the Canadian TV series Sort Of, about a trans woman who is a nanny for her friend's two kids.
I was also surprised I had missed Spaced, a kind of surrealist sitcom starring Simon Pegg and directed by Edgar Wright (think: Hot Fuzz, Shaun of the Dead). Not sure it counts as obscure or lesser-known, but it was for me anyway.