My main distro for years has been Mint, but I play around with a several others frequently. For me, it comes down to the package managers I feel most comfortable in (I know apt the best, but I know zypper and pacman ok enough to get by) and the window manager integration. Personally, I prefer Cinnamon and I think Mint has the best integration for it. My only complaint with Mint lately is the difficulty of getting nvidia drivers to work properly. It should be as simple as selecting the driver you want in the driver manager, but secureboot complicates things a bit.