Respectfully, I'm not sure you are appreciating just how expansive the realm of materialist analysis is, considering it's just applying the scientific method to understanding the world. If it can be observed, it can be analyzed. I don't reject the notion of that you'll never quantify everything, but I also don't think it's worth it to let unknowns paralyze us in our actions when we're in such a dire situation, out of time, and 95% sure of our course.