Okay, so it's a slur against robots, droids and other synthetic life. It isn't too much of a stretch therefore, to understand its use against those with prosthetic limbs etc.

To be honest we are against the uses for both meanings, as it seems like it's just yet another excuse to use a slur because it's something people hate.

We can crititicize 'AI', 'LLMs' without resorting to words like "clanker", "slop" etc.

Such things distract from actual critique anyway, and even if we want to use more vitriolic words then words like "trash" (to describe their output) already exist and avoid veering either into, or dangerously close to, slur and bigotry territory. :)