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How dangerous is it to not have any sex hormones (androgens)?
(self.asktransgender)
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Very, it can make your bones brittle and make it very hard to heal. Many trans people can't produce their own hormones and have other health issues. I know one person that was intersex (had no hormones past age 20 due to something) and was close to losing their entire jaw in their mid 20s because of how brittle their bones were. They got better after they fixed their hormone issues.