imo that's a stupid sentence that doesn't say much. It supposedly means something like "there are certain circumstances that I/you/we would like to change, but there's nothing any of us can do about it", and I agree that there is a ton of things that are outside our control, but I do NOT like the sentiment this sentence oh-so-often transmits that we are all incapable of doing anything when things become rough.

The path we take in life will never correspond to the one we dreamt of, and it will stray away from it, as it already has many times, in ways we cannot yet imagine. However, that is not (and will never be) a good reason to give up. Because it's in the face of adversity that we shine the brightest. And if you want to dazzle, OP, it's now more than ever that you must fight your struggles with all your strength. Bring it on!