I ran 2 tables in 4E, but when 5E came out they never wanted to go back.
It all came down to keeping track of all the powers, nobody liked that. They also hoarded their encounter and daily powers, rarely using them (and hoarding encounter powers doesn't make a lot of sense).
I was a little disappointed because the one table was about to hit their paragon paths, which seemed like fun, and the players seemed excited for. It's a concept I wouldn't mind seeing in a new game – it was a little like choosing a subclass at 10th level.
You're not dead when you're petrified, either, which can lead to some pretty interesting exploits, rules-as-written.
Petrified creatures count as creatures, not objects, so rules-as-written you can determine if a statue is a petrified creature by trying to target it with a spell that requires a creature for a target.
With the cantrip Poison Spray, you can check for petrified creatures without using spell slots or risking damaging the creature, since it would be immune to poison while petrified.