No not really. I mean you could never connect to the internet I guess. But that's the best mitigation there is as long as your using windows. Or run it in a VM?
So you can understand how this works, each device in your computer has a uid or hid, a unique id, or hardware id. This remains consisten as long as you have the hardware. Things that have this are like hard drives pcie cards, etc.
There's also just the fundamental unique ways your PC is built. Of all windows users how many have an Nvidia card? 90% of those 90% how many have the same drive configuration. 5% of those how many are running Intel CPU. Etc etc...
You are sadly very unique.
Check here: https://awesome-selfhosted.net/
And do a ctrl-f and look for calendar