I use Ardour. It looks pretty complicated to use at first glance, but everything you would need is there in one of the four modes in the top right corner.
I've tried Reaper for the plugins and the generally good reputation, but I couldn't understand the empty interface whatsoever.
I kinda wanna try Gentoo just for the experience, but as someone who already uses Arch, I'm worried it will take up more of my time than my current setup already does.