I use Navidrome. Really well made clients for anything, ability to select transcoding method (or lack thereof) based on a client, changing of following songs etc.

I use Plexamp

I use navidrome, it's pretty simple to setup and use and has support for many clients. For mobile I use Ultrasonic and sonixd for desktop

I've been using Plex and Plexamp for ages. I have about two terabytes of flacs in my NAS, and Plexamp seamlessly encodes it to 128 kbps Opus when listening on a mobile network, or streams the flac as-is if on Wi-Fi. It has a good recommendation engine and a very nice UI. Worth the money, if you ask me.

I used Jellyfin with Finamp on my phone.

May not be the fanciest, but I use MPD.

When I'm home, it outputs to a pipe that feeds Snapcast for my multi-room audio. If I'm away, I can stream it through MALP on Android or through a web interface (myMPD)

Jellyfin a million times over. It manages all your music and has get integrations and apps.

I have one /media/music folder which I have connected to both Jellyfin and Gonic (Subsonic). I use Gonic because it's lighter weight than Navidrome and I don't care about a web interface.

FinAmp is the nicest iOS music client I've found, and it only works with Jellyfin. On the Mac I recently started using SuperSonic (which is simple but has been more reliable for me than sonixd) which uses Gonic.

play:Sub is the most polished iOS SubSonic client, but I find the UI fussy and hard to use one-handed. Amperfy, SubStreamer, and Soundwaves are all worth trying but each frustrating in their own way. I like Amperfy the best at the moment.

Navidrome has been a revelation for me, I use it along with the absolutely brilliant app Symfonium. It took me a long time to get here, but it's a killer combination that does everything I want it to do. It has been so seamless that I had to look up what it was called because I haven't had to tinker with it for months. Tailscale works well as a VPN solution too if you need one, but you might be fine with reverse proxies etc. (popping my lemmy cherry with this comment btw)

I switched to Airsonic Advanced, after I decided that my Subsonic instance was too old (but it still worked). It works pretty well regardless of client and has a decent but not amazing web interface.

I also tried Navidrome, and found it pretty slick, but does sorting by metatags and I have some pretty old stuff that doesn't have very accurate/clean tags, so I stuck with Airsonic since it sorts by folder structure

What features do you need? ReadyMedia aka MiniDLNA will do just fine if you use a UPNP-compliant player.

Also Jellyfin, but I use a paid app, S2 player. Been the best out of all I've tried so far. Can even aggregate with local music stored on the phone.

If you're interested in a self-hosted Fediverse platform for music streaming, you can try out Funkwhale. Though I personally feel like the subsonic compatibility is pretty underwhelming, which makes it annoying to stream music from a phone with a subsonic client.