I made this recently because I want to get rid of my work MacBook Air M2 dependence and looked or something comparable.

Basically, with the Tuxedo you have a little more options regarding the graphics. You can add an RTX 4070 instead of the 4060 and the panel has a 240 Hz refresh rate. If you intend to do some gaming or need more GPU power, this may make a difference. On the other hand, if you need more battery time, a slower refresh rate might be favorable. The Tuxedo one is a little bit dimmer as well (350 nits versus 400 nits).

Tuxedo control center might be another thing to consider. According to the reviews I looked at, it works really well and Tuxedo offers proper hardware support for their system, having their own people to contribute to the code base and fix things.

I think the 16" are pretty on par between the two manufacturers. You can find more considerable differences in the 14" models, where Tuxedo offers a dedicated graphics card and Slimbook doesn't.