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We Just Got More Evidence That Long COVID Is a Brain Injury

The exact nature of long COVID is still coming to light, but we just got some of the best evidence yet that this debilitating condition stems from a brain injury.

Using high-resolution scanners, researchers at the Universities of Cambridge and Oxford have shown microscopic, structural abnormalities in the brainstems of those recovering from COVID-19.

Signs of brain inflammation were present up to 18 months after first contracting the SARS-CoV-2 virus.

"We show that the brainstem is a site of vulnerability to long-term effects of COVID-19, with persistent changes evident in the months after hospitalization," the authors of the study conclude.

https://doi.org/10.1093/brain/awae215

#health #science #biology #news @science@lemmy.world @science@beehaw.org @news@lemmy.world @health@lemmy.world @usnews@beehaw.org

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[-] Grandwolf319@sh.itjust.works 104 points 3 days ago

I think it’s important for people to realize:

A very bad cold or flu can totally damage your body and is how lots of older folks go unfortunately.

Covid without a vaccine would have been a terrible sickness.

What bugs me the most is so many people who don’t understand logical fallacies kept saying just wait a year or two and you’ll see mass deaths and weakened immunity… and they are conveniently silent now, probably blaming fires on DEI or something stupid like that.

[-] Klear@lemmy.world 16 points 2 days ago

A very bad cold or flu can totally damage your body and is how lots of older folks go unfortunately.

That was my view of COVID at the early stages of the pandemic. A lot of people were saying that it's just a bad flu. I thought it being a bad flu is terrifying.

An even so, having caught the damn thing three times now even through vaccines, I think my view back then was overly optimistic.

[-] teawrecks@lemmy.world 10 points 2 days ago

I got it before the pandemic shut down. in February of 2020. I was working in a high contact environment with high risk. I ended up sick, then sicker, then my whole team was sick, and out of work. we were told to do training as wfh and we'd be back when we felt better. it felt like that wasn't coming. I got sicker and bedridden, my dr prescribed a steroid inhaler and wasn't sure what it was. then sent out some labs and said 'inconclusive'. i stayed sick. moving from the bed into the attached bathroom and back was a 4 steo with breaks sitting on the floor process. i lost my job. i went on unemployment. it was another half of a month before I went back to the doctor. Covid. and they had no options for me but to wait it out. it wasnt bad enough.

[-] MolecularCactus1324@lemmy.world 10 points 2 days ago* (last edited 2 days ago)

I got walking pneumonia last year. Took some antibiotics and got rid of it, but it basically brought back my childhood asthma. I’ve been stuck with it for about 10 months now. Really eye opening to me how long it has lasted.

[-] cows_are_underrated@feddit.org 5 points 2 days ago

They are seeing all these mass deaths. According to the antivaxx crowd almost every single person who gets sick or dies could have prevented this by not getting vaxxed. They don't care, that this is absolute bullshit.

[-] scarabic@lemmy.world 32 points 3 days ago

These people are addicted to this feeling that they have discovered some secret that destroys conventional wisdom and sheds a whole new light on everything. They are addicted to this feeling that they’ve found a big lie everyone’s swallowed and they’re going to spit it out.

Every part of their worldview has to have that quality or they can’t hold onto it with their brains. There’s a great deal of straightforward, plain-as-day information that’s totally missing from their worldview because it doesn’t contain the drug their brain is addicted to.

[-] Furbag@lemmy.world 5 points 2 days ago

My theory is that the type of person who falls for conspiracy nonsense is the same type of person who also succumbs to solipsism. They have a core belief that they are the protagonist of their own story, and their story can't be plain, humdrum, or boring like their daily lives had been up until the moment they "uncovered" the grand plot to deceive the world. Acknowledgement of the fact that they are not special or somehow inherently different from any other individual is psychic death, so they retreat into safe spaces and echo chambers that validate them, which make them easy targets for pseudoscience and quasi-religious beliefs.

Conspiracy allows them to indulge in the fantasy of grandiosity, while also introducing them to a community of like-minded people who will welcome them and their beliefs, and never challenge them. That makes it all the more difficult for them to break out of the spell, even when presented evidence that runs contrary to what they believe.

[-] scarabic@lemmy.world 5 points 2 days ago* (last edited 2 days ago)

Yep, agree. What makes this more complex is that movie culture has relentlessly programmed all of us to think this way for decades. I don’t think it’s just a case of genetic predisposition toward solipsism, though that is surely in there as well.

Virtually all blockbuster movies and many smaller ones are about some kind of chosen hero who shatters a corrupt system, often with a single act of redemptive violence (killing the bad guy, destroying the evil machine, etc).

From Star Wars: A New Hope to The Matrix to The Hunger Games this formula has been virtually the same. It’s so relentless and consistent, and people grow up on it from an early age. Is it any surprise, with this kind of programming, that people grow up lacking the will to dedicate themselves to making a small contribution toward incremental change? No. They need shattering upheaval that saves the world, and everything less is complicity in the evil of the system.

As Zizek said: you never get to see what the hero does the day after shattering the machine. How do they rebuild a better society? Okay, redemptive violence, then what? Popular culture has no answer to this. In real life it’s about compromise, hard work, incremental improvement. But we have generations of people who’ve been fed compelling narratives about everything but that.

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[-] Zero22xx@lemmy.world 13 points 3 days ago* (last edited 3 days ago)

conveniently silent

Always. When the previous conspiracy theory / rapture date / return of JFK / illuminati plot doesn't turn out to be true, there's no talking about it or self reflection, it's just right onto the next conspiracy theory / rapture date / return of JFK / illuminati plot.

This should go both ways. What about :-

  • Wuhan Lab leak possibility

  • US sponsoring foreign GoF research

  • Assange assassination plans

  • Phones and tvs listening on conversations (Weeping Angel)

  • NSA recording all internet traffic

  • Remote car jacking

  • McDonald's ice cream breaking on purpose

Etc.

[-] rumba@lemmy.zip 2 points 2 days ago

This should go both ways. What about

The only one of those that was seriously surprising was Prism. We didn't expect the tech to be able to exist yet. It was one of those "if you put enough money into it you can do it" buckets.

OP's examples are literally impossible.

It's not that any are surprising. It's that initially they were all conspiracy theories.

[-] rumba@lemmy.zip 1 points 1 day ago

Definition: a theory that explains an event or set of circumstances as the result of a secret plot by usually powerful conspirators

also : a theory asserting that a secret of great importance is being kept from the public

Those aren't all conspiracy theories. Those aren't all even true

The Wuhan findings led by a Republican Inquisition team with an agenda and is hotly contested.

Remote car hacking was never a conspiracy theory. It's a vulnerability, it's not there on purpose or put there by a super secret plot. It wouldn't even make sense as a conspiracy theory.

McDonald's doesn't break their ice cream machines on purpose. J.M. Taylor just refused to give them access to reset system errors related to real problems and operation.

The Wuhan findings led by a Republican Inquisition team with an agenda and is hotly contested.

Four agencies still lean toward the natural origin source, while the FBI and DOE still lean toward a lab leak. Two others, including the Central Intelligence Agency, have not made assessments.. The point here is that a lab leak is no longer a debunked conspiracy theory.

Remote car hacking was never a conspiracy theory.

This is what people always say when a conspiracy theory turns out to be correct

McDonald's doesn't break their ice cream machines on purpose.

However McDonald's does force their franchises to buy a particular piece of equipment that breaks easily and head office have an exclusive contract with.

[-] rumba@lemmy.zip 1 points 1 day ago* (last edited 1 day ago)

Definition 1: a theory that explains an event or set of circumstances as the result of a secret plot by usually powerful conspirators

Definition 2: a theory asserting that a secret of great importance is being kept from the public

The point here is that a lab leak is no longer a debunked conspiracy theory.

You want a conspiracy theory? Republicans have a narrative to drive and they're in all the committees and are still running several of those agencies. There's a disagreement at best that it did or didn't happen while the people investigating have a stated agenda. That is not, by definition. Debunked or Debunking.

This is what people always say when

See definition 1 and 2

However McDonald’s does force their franchises to buy a particular piece of equipment that breaks easily

See definition 1 and 2

There's a disagreement at best that it did or didn't happen while the people investigating have a stated agenda. That is not Debunking.

Daszak effectively silenced debate over the possibility of a lab leak with a February 2020 statement in the Lancet. “We stand together to strongly condemn conspiracy theories suggesting that covid-19 does not have a natural origin,”

Peter Daszak is a British Zoologist. Not a Republican politician.

[-] rumba@lemmy.zip 1 points 1 day ago

yup, he's anti-conspiracy which is correct.

it wasn't a conspiracy that was proved to be a conspiracy

Finally we agree. Like everything else in the above list, this is a theory that was claimed to be false that later turns out to be correct.

The lab leak conspiracy hypothesis was initally denied by the lead investigator, Peter Daszak, and now turns out to be highly probable (almost certain given the lack of zoonotic spillover evidence).

[-] Chadus_Maximus@lemm.ee 2 points 2 days ago* (last edited 2 days ago)

Ofc it goes both ways. To them, everything you listed is basically truth. Something so obvious everybody knows (ok maybe not the ice cream machine). They need a bigger conspiracy. Something most people would never believe.

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[-] jawa21@lemmy.sdf.org 84 points 3 days ago

Look, I know this isn't exactly the most appropriate community to post a comment like this. I do however need to say as someone that has had debilitating brain fog for a couple of years thanks to covid: "...fuck."

[-] Emmie@lemm.ee 24 points 3 days ago* (last edited 3 days ago)

It sucks but the recovery is still possible. I imagine gaslighting and not taking it seriously by people is debilitating.

When you suffer a brain injury from a stroke everyone will be supportive and offer help but when it is long covid people will be like “what? you are probably imagining things” both aliments are recoverable but it must suck to be constantly denied and not treated seriously

[-] bluewing@lemm.ee 20 points 3 days ago

That makes 2 of us. Been living with brain fog, memory loss, inability to pick out words when speaking, and now I set something down on a countertop, turn around, turn back and look and I literally can't see the item I set there. I see everything else, even the countertop where the item is sitting. Generally I either panic or I get pissed at myself for being so stupid. And then all of a sudden, the item magically returns to view as a stare at it.

Oh, and just for fun, breathing is still hard. And all medical testing shows my lungs are just fine and there should be problem. My pulmonologist tells me I'm one of the lucky few to be so chosen-- in jest. (I had to search "lung doctor" because I couldn't remember the word pulmonologist just now)

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[-] Boomkop3@reddthat.com 19 points 3 days ago* (last edited 3 days ago)

You're fine, it's anecdotal but perspectives are still nice to see sometimes. Quite a few people around me had the same issue, a few died. (Yes, they had refused the vaccine)

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[-] Hamartiogonic@sopuli.xyz 147 points 3 days ago

Better not get vaccinated, because the vaccine kills you and covid is just another harmless flu anyway… oh wait.

Seriously though, antivaxxers already have some sort of psychological issues going on, so adding a literal brain injury to the list might not even make a big difference at that point.

[-] flicker@lemmy.dbzer0.com 48 points 3 days ago

I went looking for data, because my knee-jerk was to assume people who get vaccinated are more likely to live, and thus more likely to get long covid.

But here's what I found. The researchers found that the rate of new Long COVID cases declined with each variant, and that the numbers of cases were significantly lower in the vaccinated cohorts.

I'm just adding to the discourse.

[-] Hamartiogonic@sopuli.xyz 20 points 3 days ago

Indeed! Too bad facts don’t work when talking to conspiracy theorists. Regardless, that’s an interesting observation to the rest of us.

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[-] Wiz@midwest.social 29 points 3 days ago

COVID makes you dumber, but what happens if you start out dumb?

[-] ZeffSyde@lemmy.world 27 points 3 days ago

The current administration awards you a place in office.

[-] Hamartiogonic@sopuli.xyz 17 points 3 days ago

Even lower intelligence score? As far as D&D rules are concerned, you would get knocked unconscious if your intelligence drops to zero.

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[-] MooseTheDog@lemmy.world 33 points 3 days ago

I knew a conservotard type. He never ventured out from his rural area so he never had to change his mind. He didn't believe in COVID of course, until he lost all taste of food. I genuinely feel bad for the guy. He said everything smelled or tasted like shit. It was 3 months before he started tasting again. After that I laughed at every anti-COVID nut in my life pretty openly.

[-] GuitarSon2024@lemmy.world 8 points 2 days ago

The biggest problem with social media is that it united the village idiots like your pal. Now, instead of being fringe, they find like minded dipshits online who reinforce their belief while also feeding them new, insane, ideas. I don't know where it's leading us to, but so far it ain't good.

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[-] TheOctonaut@mander.xyz 54 points 3 days ago

Well yeah, that's where the chip goes

[-] BJHanssen@lemmy.world 21 points 3 days ago

I believe the signs have always pointed to it being a one-two punch of lingering inflammation and actual lasting physical damage to the blood vessels, including in the brain. The fatigue symptoms dissipated for me after about a year, but the inability to focus and the shite memory has not and likely will not go away. Also my muscles got fucked by the rhabdo and my EDS got much worse, but hey…

Every new piece of scholarly evidence is good to have.

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this post was submitted on 15 Jan 2025
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