"refrigerate" at least has sensible etymological roots in its constituent components.

The problem with brain rot lingo is that it isn't constructed from precedent but a decay therefrom, corrupted by niche "meta" references that are little more than inside jokes that escaped their in-group, divorced of the context that brought them about.

...

Then again, though, the most popular word that humans speak all over the world is "OK", which is itself a memetic corruption of a fad, wherein people were saying "All Correct" with a deliberately exaggerated fake British accent: "Oll Korrect" (which became abbreviated).

And brain rot does have the fact that it's very funny going for it. It sounds silly which makes it fun to say and it pisses people off which makes it even funnier, because getting mad about it is a drastic overreaction. So I don't think it'll even really BECOME an actual serious problem, because the moment it hits mainstream and corporations start publishing commercials about "skibidi Ohio GYATT" it's going to implode like "it's morbin time" burned Sony.

Otherwise, constructing new words out of extant etymological particles is DELIGHTFULLY useful. In Minecraft, I built an Enfenestrator:
A window through which zombies throw themselves into a catchment chamber for culling and (when zombified villagers are isolated) curing.