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Police Narcan pitbull puppy O.D.ing on Fentanyl in Walmart parking lot
(www.latimes.com)
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Unsure of the specific pharmacokinetics behind it but dogs take about 3x mcg per kg dosing compared to humans. A lethal dose of fentanyl for humans is 100-200 micrograms which would theoretically translate to about 600mcg lethal dosage for dogs. Considerably larger than a humans tolerance but still only a few granules of powder would be lethal