edit:
I've updated & expanded the list (finished for today)
From Wikipedia, the free encyclopedia
Linux is a family of open source Unix-like operating systems based on the Linux kernel, an operating system kernel first released on September 17, 1991 by Linus Torvalds. Linux is typically packaged in a Linux distribution (or distro for short).
Distributions include the Linux kernel and supporting system software and libraries, many of which are provided by the GNU Project. Many Linux distributions use the word "Linux" in their name, but the Free Software Foundation uses the name GNU/Linux to emphasize the importance of GNU software, causing some controversy.
Community icon by Alpár-Etele Méder, licensed under CC BY 3.0
From my very short experience so far. It really depends on how deep you want to go and what your use case is. If you just want to install applications and use them then it's not really any different than installing them via terminal on other distros. You just make a list of the app names in a config file and then rebuild and can go about your day.
If I'd wanted to use my laptop with NixOS as my Fedora desktop then I'd be done setting it up 5min after I've installed the system. The only time I touch terminal on my Fedora system is when I turn on PC and check for updates because it's faster than waiting for Software to refresh.
Probably the biggest benefit other than reproducibility is that you get immutability without reliance on flatpaks.