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this post was submitted on 30 Jul 2026
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What is different about AB type from females? That describes me and I've almost earned my 2 gallon pin, the ladies in the blood mobile are always happy to see me.
AB type females can develop dangerous antibodies during pregnancy, and so even if you’ve never been pregnant (or think you’ve never been pregnant) there is still statistically an additional risk because there’s no good way to know for certain whether you’ve has ever been pregnant. The tests and screening for blood antibodies are expensive. Because of the heightened risk, taking AB positive female blood can be more expensive and complicated than it’s worth, so many blood banks just don’t actively encourage AB females to donate as often. There is still use for any kind of blood, even if it is used for research or if they use the RBC and waste the plasma. They certainly would never turn you away, but they also won’t regularly pester you the way they will an O- or O+ donor
AB+ male donor plasma is compatible with all blood types (universal plasma donor) and so they really want that. They call it liquid gold
I don’t know enough about blood banking specifically but it’s possible that there are some blood banks who have better capacity to screen any female AB plasma for HLA antibodies and so they don’t care as much. Idk. I just know as an AB+ female, my local blood bank was like “Don’t donate unless we tell you we need it”
Fascinating, cool to know, thank you. I will ask about it next time i donate.
I googled it and this is from blood.co.uk:
Interesting. Thank you for googling for me, I guess I could have done that. I'll probably google a bit more and maybe add the info here just for infos sake, because this seems to be referring just to ab- and I'm ab+
Personally, I've never been pregnant, but it sounds like the antibodies might still be present even before pregnancy.
The bloodmobile/bank where i donate is ALWAYS desperate for blood, and I've never read or heard anything about this exclusion in my 17 years of donating, the only time I've ever been turned away is for low iron.
Oh it’s not exclusionary. They’ll totally still take your blood. It’s just in the lowest demand in general, and blood banks often tell AB females (both + and -) that they will reach out when they want/need blood donation, rather than telling those donors to come for donations as often as possible like they do for other donors. If you’re willing to donate, by all means keep donating. The blood banks can figure out what to do with it and all blood has its uses!