Very unlikely. In medication trials, it's usually comparing the new medication against the known existing treatment. No medication is both not considered ethical, and wouldn't tell you very much, because what you're testing for is whether the new medication is better than the existing treatments, not whether it works to begin with. You have to show that it does to justify doing the study in the first place. Ethics regulators would not permit you to prevent people from getting any treatment in a study.

The sad thing is that medication just doesn't work sometimes, especially for something as variable as cancer. That's the other side of joining an advanced program. Sometimes, it turns out that the treatment isn't effective for some kinds of cancer, or for some people. If it was perfect, and passed that stage, it would be the normal treatment, not a trial.