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You probably can't trust your password manager if it's compromised
(www.theregister.com)
This is a most excellent place for technology news and articles.
It's clearly a risk, but if you have dozens of accounts and passwords it's hard to come up with a feasible alternative.
my solution is to make variants of my usual password that are so different I end up having to reset my passwords constantly. Lately, I've taken to writing my passwords on a piece of paper in my house, which means I can choose more unique ones