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I'll start.
It's tragic how many terrible things that President "Smokin' Diamond" Joe Biden has had to allow to pass because there simply isn't enough of a majority to overcome GOP opposition to everything. If only there were some common-sense bills could be passed, with bipartisan support, then maybe we could remember that this country is already great, mend the divide, and get back on track.
spoiler
(FUCK. That hurt to write, including the "the entire world is Burgerland" presumptive delivery. I need a shower.) 
I'm as left as they come, but I don't think focusing on trans issues is worth it for any progressive politician. Trans people are only a small percentage of the population, so most people won't care their problems and they can't form a large voting bloc.
And honestly, most people are alienated by the extreme actions of trans activists. There's more nuance to this issue that can't be condensed into a simple slogan like ”trans rights are human rights”. J.K. Rowling has had some valid points, but has been unfairly silenced by the trans rights mob. Sure, last week she may have retweeted some anti-trans opinions by that guy who had a Nazi flag banner and the 14 words in his bio, but we all make mistakes.
I've seen enough sensationalized, cherry-picked headlines to know that there's a real problem with offering ”gender-affirming care” to children. I also learned about the issue from a YouTuber who looks at it from a woman's rights perspective; I know some of you are already wanting to childishly slander her by saying she's a TERF, but you should really check out her videos. Here's the channel: