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Mathematics disproves Matrix theory, says reality isn’t simulation
(interestingengineering.com)
This is a most excellent place for technology news and articles.
But you wouldn't have to simulate the whole universe, only one brain. There is no way for you to know, if everything your brain experiences is caused by it actually happening, or just the neutrons being triggered in that way from outside.
Solipsism is definitely one way to look at it.