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Results: In the fully adjusted model, significant positive associations between P_CARB and CVD risk were observed in the pooled analysis, showing that the HRs (95% CIs) for CVD across increasing quartiles of P_CARB were 1.00 (reference), 1.16 (0.94-1.44), 1.25 (0.96-1.63), and 1.48 (1.08-2.03). The restricted cubic spline regression analysis confirmed a linear dose-response relationship between P_CARB and CVD risk in both cohort studies, with all p-values for nonlinearity >0.05.

Conclusion: Our findings suggest that a carbohydrate-based diet high in proportion to total energy intake may increase the risk of CVD among middle-aged Korean adults, underscoring the importance of balanced macronutrient distribution. However, more research is needed to evaluate the sources and quality of carbohydrates in relation to CVD risk in this population.

Full Paper: https://doi.org/10.1016/j.clnu.2023.06.013

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[-] TootSweet@lemmy.world 2 points 1 day ago

Mostly what I meant was more that every kind of calorie source is vilified by someone who imagines themselves an authority. I probably should have put each of those sentences in quotes or something make it clear I wasn't stating them as fact, but just as the sort of thing that people say. But, to talk about where I've heard these things mentioned:

  • Yeah, I know there are a lot of objections to the claim that saturated fat causes heart disease. I don't really avoid saturated fat myself.
  • The bit about unsaturated fats, I was being a little bit imprecise conflating PUFAs with MUFAs while also leaving out any free radical involvement and arterial plaque. But I'm sure I've heard random folks on, say, Robb Wolf's podcast (a long time ago) advocating for avoiding PUFAs in favor of saturated fats based PUFAs being more susceptible to oxidization by free radicals. (Not saying that source was a particularly good or bad one. Just driving home the point that there's no calorie source you won't find vilified by someone.)
  • Trans fats being poison isn't even controversial now-a-days. Heh.
  • With the protein and kidneys thing, I'm referring to "The China Study". My understanding is that its results were taken by some to indicate protein could cause kidney problems. Also, my grandmother's nephrologist had my grandmother limiting her protein. (And, of course, there's also a big difference between the claim that high protein causes kidney problems vs the claim that high protein can exacerbate existing kidney problems. But yeah. Also, I don't put enough stock in those claims to try to limit my protein intake.)
  • About carbs, there are definitely organizations that at least at one time advocated for high-carb diets. And you could definitely see where a lot of people could get the idea that carbs=good, fats=bad.
  • About glucose, some carbs do metabolize to fructose.
  • Fructose metabolizing like ethanol and causing liver dysfunction is still pretty controversial in the mainstream nutrition community, right?
  • Alcohol's not controversial.
  • And of course starving to death is bad.

Calories-wise, in my own diet:

  • I avoid sugars (including basically any fruit sweeter than a tomato or red bell pepper) like the plague. And yes that's because I think they're terrible for you. But also, I have violent acute symptoms when I imbibe, which... is kinda good thing to some extent. I've got a feedback mechanism. I don't know whether it's glucose, fructose, or sucrose that gives me symptoms, but I avoid all of those. I don't think things like dextrose or artificial sweeteners (which of course don't have calories, but anyway) would give me the acute symptoms, but I don't eat any of those either.
  • Carbs are a sometimes thing. Usually they take the form of white rice, sweet potatoes, or russet potatoes. (Because those metabolize only to glucose and I have a history of NASH.) I do high carbs no more than once a week.
  • The meats I eat are mostly sardines, pork, and chicken, but I don't really avoid beef. Neither do I avoid the fattier cuts of meat or anything.
  • I eat eggs quite a lot.
  • I do eat a fair amount of olive oil, but seed oils aren't anything I'd eat except extremely rarely. And I don't avoid butter.
  • Of course, fuck trans fats. And I've never drunk alcohol.
[-] jet@hackertalks.com 2 points 17 hours ago

Fructose metabolizing like ethanol and causing liver dysfunction is still pretty controversial in the mainstream nutrition community, right?

I've seen no controversy here, the metabolic pathway is the same, its mechanical and observable. There are people saying whole fruits are a net-benefit in-spite of this. But I haven't seen any serious advocate pushing for high fructose corn syrup as a health food.

I have violent acute symptoms when I imbibe, which… is kinda good thing to some extent. I’ve got a feedback mechanism

It's nice to have feedback!

this post was submitted on 02 Oct 2025
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