ReGenesis. They did that whole pandemic thing waaay before it actually happened and Peter Outerbridge was fucking awesome in it. Four seasons of a great show about bioterrorism, mysterious diseases and environmental changes - I believe it still holds up today.

That guy collapsing in the intro with blood coming out of his nose is still such an awesome shot.

When it came out, they accompanied the series with a webgame (in 2004) and went extremely overboard with it:

An exploratory game, the ReGenesis Extended Reality draws viewers into a conspiracy and mystery that weaves in and out of the TV series, using the internet, email, and other media to immerse the viewer, blurring the line between fiction and reality. ReGenesis Extended Reality harnesses the power of enthusiastic fans that seed the site with discussion content and collaborative investigations. Extensive knowledge of various chemistry and biotechnology issues is required to find out why the plot in many episodes can't be true (if it can't).

I wish I could've experienced that, but when I watched the series, it was already shut down.