Hey guys and gals!

I have a very back-tire heavy setup. Basically I have my tent (without poles, my GF carries those) strapped to the handlebars and everything else in the panniers on the back rack and on the rack (it's a Vaude Karakorum Pack, to be precise). Do I have to keep anything in mind to reduce wear and tear on my back wheel or tube? I know the weight distribution isn't optimal but it's just so convenient to have only one real bag instead of a myriad of smaller ones. Also cheaper. Still, curious about the drawbacks and how to counter them. Thank you!