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The ISS is 'too clean', and it could be making astronauts sick
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Humans aren't built for 0g, and I expect we will never live whole lives like that. But living in space does not require living in 0g.
I'm quite certain that if humans manage to survive and continue to thrive for another 200 years, we will absolutely be living in space. And at that point it will be inevitable that the number of humans living in space will eventually come to dwarf the number living on planets.
Gravity isnβt the only issue. Radiation and cosmic rays are a much bigger problem than that. Psychological issues from being in cramped ships for so long. Food production. All sorts of other crap, too.
Radiation isn't that big a deal. If you have a large enough structure for a colony, or even large enough for 50 people, then you have plenty of mass for radiation shielding. At that scale it's a non-issue.
Well, only at first... Families don't want to live in cramped ships, so they won't. They'll live in artificial habitats with grass and open spaces. Eventually they'll be large enough to have rivers and mountains.
But even without all that, just ask anyone who's served on a submarine if it's possible to survive in cramped quarters. It's doable.