Higher global temperature and more drastic weather. Better medicine and medical equipment but with higher costs. Decreasing global population, but more homeless people due to ai software and physical bots. The continually profitting billionaires will control more of the media to influence those below them, ie to have them fight among themselves rather than them. Probably more in "goverments" for more control. Continuing wars just different countries for profit.

This won't be that big of a difference within that timespan, but the trend will continue as more time passes.

I try to be an optimist, but unless the underclass revolts, it's hard to see otherwise.

There will be a lunar spacestation, according to NASA, which I'll be looking forward to seeing, at least.