I loved Alice from Spiritfarer. I kept her around for way too long. Sorry Alice, I know you were ready but I wasn't.
For me, it was Astrid. Watching that fiercely proud, brutally honest and deeply caring warrior lady slowly lose the will to live after Giovanni was gone ... that hit hard for some reason. And her reassuring Stella that is "isn't so bad to be alone" and the like didn't make it better.
Witcher3 upon finishing Blood&Wine - there was such a void in my life after the closing scenes. Like I’d just watched my best friends move away across the world, knowing that I would probably never see them again.
Hellblade Senua's Sacrifice
I found the premise of exploring the psyche of Senua and after the end, even though she isn't fixed, she can at least put a part of herself to rest and really rings home what she as a person and people like her can be living with.
Spec Ops: The Line
Getting through the game and then evaulating all your decisions and seeing the changes over time of a broken man getting more broken leaves an impression of "Are we the bad guys", especially after seeing the tone change from dialogue, loading screens and even how the characters move and animation over the course of the game.
Lee from the Walking Dead game by Telltale, your character in Knights of the Old Republic, Abe from Oddworld: Abe's Odyssey, Octodad, and Ricky the sock puppet from My Friendly Neighborhood.
The Blackwell series.
Night in the woods
A gaming community free from the hype and oversaturation of current releases, catering to gamers who wait at least 12 months after release to play a game. Whether it's price, waiting for bugs/issues to be patched, DLC to be released, don't meet the system requirements, or just haven't had the time to keep up with the latest releases.
^(placeholder)^