Is this the first human trial, or just the first officially sanctioned one?
IIRC there was that one guy who experimented on himself and cured his lactose intolerance.
... found it: https://www.youtube.com/watch?v=J3FcbFqSoQY
Nearly 8 years ago.
I feel obligated to mention that he doesn't modify his own genes, he infects himself with a modified bacteria that produces lactase.
you can just eat yogurt to get the same results
Wait is that true? I would totally eat yogurt if it meant I could enjoy ice cream again.
First-in-human just means it's the first time that specific therapy is being tested on humans instead of animals (e.g. mice, dogs, monkeys), and the primary objective of the trial is to test that it's safe for use in humans. It doesn't refer to the concept of gene editing or lowering cholesterol.
was safe and reduced LDL cholesterol by nearly 50% and reduced triglycerides by about 55%
From the referenced article
What is the point of your comment?
Thought emporium?
Yep thought emporium.
~~But I think the Chinese scientist that experimented on babies did it few years before that even.~~ looks like same year, 2018, and thought emporium published first by 8 months
We lowered your cholesterol. But you now have horns and crave the taste of human flesh.
I don't understand why you used "but", where it should clearly be "as well as"...
Why would you lower cholesterol?
The body literally makes it because you need it. People with high cholesterol live longer…
https://pmc.ncbi.nlm.nih.gov/articles/PMC11901585/
Youd wanna lower arterial plaque so cholesterol doesnt get stuck?
An arterial calcium scan is the best indicator for heart disease etc.
Not cholesterol.
The body literally makes it because you need it
For what?
People with high cholesterol live longer…
I don't think that's really a conclusive study. It only focuses on people who are already 80 or older and ignores the majority of people who suffer from cardiovascular issues that don't make it to their eighties because of it.
From this study you could also conclude that people who have a natural resistance to high cholesterol live longer.
Youd wanna lower arterial plaque so cholesterol doesnt get stuck?
Plaque forms when cholesterol lodges to the walls of arteries. This happens at a greater rate when you have more lower density cholesterol in your blood.
An arterial calcium scan is the best indicator for heart disease etc. Not cholesterol
But calcium buildups are formed from clacified plaque, which is made from cholesterol.....
If all forms of high cholesterol were really beneficial Americans would modern day Methuselahs.
for what?
You might not need cholesterol. But that's what brains are made out of.
Lol, so your claim is that people with excessive cholesterol levels require it because they are making more brain.....?
No is claiming you shouldn't have any cholesterol in your blood, just that there isn't reason to have an elevated amount.
If your body actually needed the excess lipids being produced it wouldn't be saturated in the blood, it would be getting used.
Maybe yours, but...
I have high cholesterol. I can send you some if you want. Promise it will make you live longer, it says so on this lemmy comment...
Is it butter or olive oil? I want to taste good when I die
You need to reach out to the scientists to let them know! You could save lives with your insight!
I'm sorry to inform you that you have fallen for online propaganda. Cholesterol definitely is bad for you.
Our results challenge the common view that longevity is invariably associated with low cholesterol levels.
While single study like this is far from conclusive, it wouldn’t surprise me to learn that a diet of mostly minimally processed plant oils and animal fats would result in better longevity than the typical Western diet comprised mostly of the “hateful 8”.
With what "side" effects?
Rich people living longer
That is indeed a very heavy side effect and could potentially be a threat to human life on this planet.
Anything not to eat less butter, huh?
This is a most excellent place for technology news and articles.
