This actually hits home a bit. My wife and son both deal with severe depression (major depression disorder). It's a challenge at times and can't say I'm not impacted by the same.

I'm not Appalachian, but pretty close to that area (Southwest Ohio / Cincinnati).

I haven't been able to solve my wife's and sons issues (both do take medication). For myself though, I find limiting certain things do help. For instance.....

#1: I've abandoned all/most forms of social media. The platforms I'm on I limit my time

#2: Having hobbies outside of tech helped balance some emotional states / burnout. Taking a interest in hiking and kayaking has been a great disconnect for me.

#3: Pay less attention to political dramas and other fear inducing platforms. I still check in on major things, but reducing this helped my anxiety and depression.

There's no one size fits all for depression. Overall loving a healthy balanced life seems key.....just easier said then done in today's world.