This sure sounds like an amazing breakthrough, RNA based vaccine that works on "all strains" of a virus and can be administered with a nasal spray...
Would be pretty amazing to not have to go get a shot annually, just a quick nose spray once and be done.
Most promises in medical news, much like energy news, never pan out.
Here's to hoping though.
In medicine, finding out what doesn't work is nearly as valuable as finding what does. Because finding out why it doesn't work can lead to you the solution and perhaps even solutions for things you weren't even looking for.
Yet another reason for journals to have a negative results publication.
finding out what doesn’t work is nearly as valuable as finding what does
Sometimes, sure. Most of the time, though, it's more akin to: "Worked on isolated cells in vitro, but doesn't approach target cells in vivo due to ECM."
Ya. Until the kooks decide Bill Gates is resting to install AI in our heads through our noses. …or some such bullshit.
"yah, mom, look I heard right here on Lemmy, Bill Gates is making a nose spray to turn us into robots"
Gay robots.
Can I meet some?
Gay frog robots.
Apparently people can’t read and for some reason decided that you’re anti vax.
I used windows once, and if you checked inside my head you'd find a neural network.
It will be awesome if this can make it to human trials and be successful. Lots of immunocompromised people could benefit from this.
Website says
"Scientists at UC Riverside have demonstrated a new, RNA-based vaccine strategy that is effective against any strain of a virus and can be used safely even by babies or the immunocompromised. "
Paper says
"Live-attenuated virus vaccine defective in RNAi suppression induces rapid protection in neonatal and adult mice lacking mature B and T cells"
I love how they probably used chatgpt to summarize the article for their website. And jumping from here to saying "this vaccine is effective against everything ever" seems a bit! over reaching. Even universal vaccines within a given subtype are finicky. There seems to be a trade off between universality (of recognition) and of effectiveness. Nevertheless this seems like a different mechanism than previous RNA/protein vaccines in that it seems to work by inducing innate immunity. Even though they say that mice remain immune 90d post vaccination, that is another area where mice and men can be substantially different, so I think we are still at the wait and see stage unfortunately.
And this joke of a sentence here
"With one vaccine injection, they found the mice were protected from a lethal dose of the unmodified virus for at least 90 days. Note that some studies show nine mouse days are roughly equivalent to one human year. "
Wohooo we are immune for 10 years!!!
Get fucked viruses!
I can't seem to find the paper, either. Hmmm... where 'tis? I emailed the article author, Jules Bernstein, to request a link fix. fingers crossed.
Link works for me maybe they fixed it?
If you want to search for it yourself it's "Live-attenuated virus vaccine defective in RNAi suppression induces rapid protection in neonatal and adult mice lacking mature B and T cells" by Gang Chen, Qingxia Han, Wan-Xiang Li, and Shou-Wei Ding
Today it worked fine. Could be on my end. VPN, script blockers, etc. shrug
And WOW this looks like a significant development.
Ya, like nature works that way...
Well it doesn't. People made it. With science.
I'm not anti vac. But, this article is pretty smug while still using the word "should". Hubris is thinking that we've beat nature.
I'm absolutely thrilled if this actually gets us to the next level of protecting people. But I'm beating down by these "savior" articles.
Welcome to /c/UpliftingNews, a dedicated space where optimism and positivity converge to bring you the most heartening and inspiring stories from around the world. We strive to curate and share content that lights up your day, invigorates your spirit, and inspires you to spread positivity in your own way. This is a sanctuary for those seeking a break from the incessant negativity and rage (e.g. schadenfreude) often found in today's news cycle. From acts of everyday kindness to large-scale philanthropic efforts, from individual achievements to community triumphs, we bring you news—in text form or otherwise—that gives hope, fosters empathy, and strengthens the belief in humanity's capacity for good, from a quality outlet that does not publish bad copies of copies of copies.
Here in /c/UpliftingNews, we uphold the values of respect, empathy, and inclusivity, fostering a supportive and vibrant community. We encourage you to share your positive news, comment, engage in uplifting conversations, and find solace in the goodness that exists around us. We are more than a news-sharing platform; we are a community built on the power of positivity and the collective desire for a more hopeful world. Remember, your small acts of kindness can be someone else's big ray of hope. Be part of the positivity revolution; share, uplift, inspire!