Mistifying / Mistification works if you like Anglo-German puns. Emmerdification for an Anglo-French equivalent.

If you're against anything to do with faeces at all, I'm not sure there's as short and easy a neologism that as fully captures the meaning and, importantly, disdain without being a mouthful.

You need an en- of some sort because it's clear that something is changing and then the action is the attempt to squeeze as much profit out of an enterprise with the expectation that nothing much will, er, change. This inevitably ruins or destroys the nature of the enterprise from the users' point of view.

Then the CEO immediately has cognitive dissonance between their own ego and self-belief of infallibility versus the fact the enterprise isn't working or has changed far more than their expectations. Their ego, and desire for profit, inevitably wins.

Much like badly managed corporate take-overs, all the smart people leave as soon as they can assuming they haven't already been fired and replaced by an inferior of some sort.

Thus, the whole thing turns to... well. Is there a better word?