What is worth?

Dollar value.

Would you rather have 500 1s or 5 100s?

Don't care. They both get deposited at my bank the same.

You already said you’d take the 100s, why?

An acknowledgement to the point you were making that was a digression from the discussion at hand. My mistake apparently.

I would take the 100s because I personally value the convenience of 100s more than the 1s, so to me, a single 100 is worth more than 100 1s.

I personally would not accept a Genie wish for either as the mass would create a black hole that would destroy the universe. There is no "practical consideration" when dealing with infinities. Knowing how to work with infinities is useful for complex mathematics, but there is no real world application until you simplify away the infinities.

Worth doesn’t need to imply the monetary value of the money.

It very much does imply the monetary value of the money. It can mean other things if you want to define it as such, but you need to before hand in such a case. It was not defined differently by OP.