So hopefully I'm doing this right! :) (I'm still new to some of this so haven't figured out things yet! I did ask this via Mastodon also, but wanted to add more detail to my answer!)
Is there a computer game, a moment in a game, a boss fight, or a specific moment that you would love to experience fresh with no prior memory of it?
Mine would have to be The Seat of Sacrifice fight in Final Fantasy XIV, one of if not my most favourite fights in the game to date.
The mechanics work so well and tie into everything that's been happening, and then that moment where <redacted> (I refuse to spoil it!) shows up to help and then leaves with I think what made me cheer SO MUCH the first time I did the fight.
The music, the song To The Edge has become one of my most played songs in my entire music library (alongside Endwalker - Footfalls and Shadowbringers) as it is quite frankly perfect for the fight. and when they revealed that Soken had been battling cancer and wrote it whilst in hospital...
I adore the fight all together, and cannot help but say the lines in the cut scene bit in the middle every time I do the fight, and will never ever get bored of it.
So what moments in a game would you love to complete again with no prior experience?
If it has to be a specific moment/level/fight/etc, off the top of my head I'd love to fight the final boss in Final Fantasy 13 fresh again. Its such a cool test of everything you've learned about the combat and a great example of how a JRPG boss can be vulnerable to ailments and debuffs while still putting up plenty of fight. There are definitely better boss fights in gaming but this was one of the most fun to learn how to do in the moment and it also loses a good bit of what makes it fun when you know whats coming.
If I'm allowed to pick a game in general, absolutely Xenoblade 1 as its my favorite game of all time. Amazing combat both in terms of system mechanics and party member variety, really fun to explore enviroments that are never annoying to fight in, and near perfect side content both in terms of amount and structure. Its replay value is insane as I've replayed it 4 times (2 on Wii, 2 on Switch) but I'd love to experience it for the first time again.