A terrible idea that will hinder everyone and not serve it's original purpose in a flash.

• anything that parse the page is broken, this includes screen reader, but also indexing, searching, and people that replace fonts locally for accessibility or other reasons
• the "solution" for accessibility is pure trash
• it can be trivially detected and reversed. I suspect LLM would be incredibly better at adapting to this than anything done manually too

It's basically a kid playing with "encrypshun" client-side, giving both the cipher and the key to the client and hoping it'll work. Or, as other put it, DRM that don't work for any of its original purpose, but create an additional layer of complexity and missing features, a common trend in modern projects.