Other image here from the US NIH history archives about the product. This one promises that Neuralgine contains no morphine, opium, or cocaine.
So what does it contain? They didn't have to tell you, back then.
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No morphine, opium and cocaine, because it already has codeine?
There’s no official record of its composition but it was theorized to contain acetanilide, caffeine, and sodium salicylate.
Acetanilide and caffeine meant it probably did work really well, but the downsides were cancer, cyanosis, and liver and kidney damage…
As the years went on, it was believed acetanilide was metabolized into acetaminophen aka paracetamol.
Paracetamol, Caffeine, and Aspirin are the effective ingredients for a very effective headache medicine in America. Neuralgine was likely Excedrin before Bayer.