Audio is a smooth sail for me these days with multiple Linux distros thanks to pipewire. Tried on multiple desktop PCs with Intel, NVidia and AMD hardware from older to newer and never had audio issues. Be it OpenSUSE, Bazzite, EndeavourOS, Arch, Mint or Fedora. All have Pipewire as the default sound system, IIRC. The integration under modern KDE Plasma is fantastic. I recently discovered Helvum which makes audio routing via a patchbay GUI really easy. Don't know if Pipewire is suited for music production though or if you still need Jack for that because of latency issues.