I wouldn't because no one's an expert in all aspects of programming, and as with any learned skill, the majority of folks are at the lower end of the skill spectrum. Some folks reading along are experts in biology and only do some light scripting to process their data, but still generally get the jokes.

But even if it were the case that this was a community exclusively for senior software engineers, it would still be legal to just explain the difference rather than throwing a quip at them.