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A place for majestic STEMLORD peacocking, as well as memes about the realities of working in a lab.

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There are human cells without mitochondria, and plenty of energy chains outside of mitochondrial action.
There are, in fact lots of them: your red blood cells, for example.
Mitochondria are more efficient at energy production, not the only source. Red cells use glycolysis.
You as a human organism would die pretty fast because you need that more efficient energy production but a lot of your cells would be fine until the effects of the system collapsing around them go into effect.
Don't think about that metaphor too deeply.